This study, supported by the U.S. Department of Defense, aims to evaluate a novel point-of-care coagulation diagnostic device developed by Levisonics, which uses acoustic tweezing technology to assess blood clotting dynamics in trauma patients. Conducted at Indiana University Health Methodist Hospital, the study will enroll approximately 150 Level 1 and Level 2 trauma patients to compare the device’s performance against standard clinical coagulation tests such as thromboelastography (TEG), PT and aPTT. The device analyzes small volumes of whole blood without contact, offering rapid and comprehensive assessment of early, intermediate and late-stage coagulation. The primary goal is to determine the device’s ability to detect trauma-induced coagulopathy (TIC) and support timely clinical decision-making in emergency settings. This preclinical study will also explore correlations between device output and clinical outcomes, with all data deidentified and used solely for research and device optimization.
