27429-Hodge, Jennelle

Jennelle C. Hodge, PhD

Professor of Clinical Medical & Molecular Genetics

Co-Director, Cytogenetics Laboratory

Associate Director, Molecular Genetics Diagnostic Laboratory

Email
jhodge1@iu.edu
Phone
(317) 274-5749
Address
975 W. Walnut Street
IB-354
Indianapolis, IN 46202
PubMed:

Bio

Jennelle C. Hodge, Ph.D., board certified in ABMGG Clinical Cytogenetics and Molecular Genetics and Genomics, is a director in the Cytogenetics, Molecular Genetics and Pharmacogenomics laboratories and a Professor in the Department of Medical and Molecular Genetics at Indiana University.

Her translational research focuses on cancer genetics and mining of genomic data for genotype and phenotype correlation.

Dr. Hodge is currently a Standing Editor for the WHO Classification of Tumours (WCT) and the Chair of the Genetics and Genomics Subcommittee. She is also the Editor-in-Chief for the Compendium of Cancer Genome Aberrations (CCGA.io); this wiki-style resource aims to provide up-to-date information on the genetic correlates to the WCT-based diseases for laboratory cancer case interpretation.

Additionally, Dr. Hodge has had leadership roles in clinical genetics-focused organizations (American College of Medical Genetics and Genomics, Association for Molecular Pathology, and Cancer Genomics Consortium), and contributed to diverse academic endeavors including high-impact publications in journals such as Cell and Nature Genetics. Her goals are to support the next generation of clinical scientists and produce resources for the genetics community.

Key Publications

Khoury J, Solary E, Abla O, Akkari Y, Alaggio R, Apperley J, Bejar R, Berti E, Busque L, Chan JKC, Chen W, Chen X, Chng WJ, Choi J, Colmenero I, Coupland S, Cross N, de Jong D, Elghetany MT, Takahashi E, Emile J-F, Ferry J, Fogelstrand L, Fontenay M, Germing U, Gujral S, Haferlach T, Harrison C, Hodge JC, Hu S, Jansen J, Kanagal-Shamanna R, Kantarjian H, Kratz C, Li X, Lim M, Loeb K, Loghavi S, Marcogliese A, Meshinchi S, Michaels P, Naresh K, Natkunam Y, Nejati R, Ott G, Padron E, Patel K, Patkar N, Picarsic J, Platzbecker U, Roberts I, Schuh A, Sewell W, Siebert R, Tembhare P, Tyner J, Verstovsek S, Wang W, Wood B, Xiao W, Yeung C, Hochhaus A. Leukemia. The 5th Edition of The World Health Organization Classification of Haematolymphoid Tumours: Myeloid and Histiocytic/Dendritic Neoplasms. Leukemia. 36(7):1703-1719, 2022.

Collins RL, Glessner JT, Porcu E, Lepamets M, Brandon R, Lauricella C, Han L, Morely T, Niestroj L-M, Ulirsch J, Everett S, Howrigan DP, Boone1 PM, Fu1 J, Karczewski K, Kellaris G, Lowther C, Lucente D, Mohajeri K, Nõukas M, Nuttle X, Samocha KE, Trinh M,  Ullah F, Võsa U, Epi25 Consortium, Estonian Biobank Research Team, Hurles ME, Aradhya S, Davis EE, Finucane H, Gusella JF, Janze A, Katsanis N, Matyakhina L, Neal BM, Sanders D, Warren S, Hodge JC, Lal D, Ruderfer DM, Meck J, Mägi R, Esko T, Reymond A, Kutalik Z, Hakonarson H, Sunyaev S, Brand H, Talkowski ME. A cross-disorder dosage sensitivity map of the human genome. Cell. 185(16):3041-3055.e25, 2022.

Landis BJ, Elmore LR, Geddes GC, Lin J-H, Yatsenko SA, Lo C, Border WL, Wechsler SB, Murali CN, Lalani SR, Hinton RB, Garg V, McBride KL, Hodge JC, Ware SM. A multicenter analysis of abnormal chromosomal microarray findings in congenital heart disease. Journal of the American Heart Association. 12(18):e029340, 2023.

Lowther C, Valkanas E, Giordano JL, Wang HZ, Currall BB O’Keefe K, Pierce-Hoffman E, Kurtas NE, Whelan CW, Hao SP, Weisburd BW, Jalili V, Fu J, Wong I, Collins RL, Zhao X, Austin-Tse CA, Evangelista E, Lemire G, Aggarwal VS, Lucente D, Gauthier LD, Tolonen C, Sahakian N, Stevens, C, An J-Y, Dong S, Norton ME, Mackenzie T, Devlin B, Gilmore K, Powell BC, Brandt A, Vetrini F, DiVito M, Sanders SJ, MacArthur DG, Hodge JC, O'Donnell-Luria AH, Rehm HL, Vora NL, Levy B, Brand H, Wapner R, Talkowski ME. Systematic evaluation of genome sequencing for the diagnostic assessment of autism spectrum disorder and fetal structural anomalies. Am J Hum Genet. 110(9):1454-1469, 2023.

Shugg T, Ly RC, Osei W, Rowe EJ, Granfield CA, Lynnes TC, Medeiros EB, Hodge JC, Breman AM, Schneider BP, Sahinalp SC, Numanagic I, Salisbury BA, Bray SM, Ratcliff R, Skaar TC. Computational pharmacogenotype extraction from clinical next-generations sequencing. Frontiers Oncology. 13:1199741, 2023.

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